Diane M Thiboutot Selected Research

Acne Vulgaris

12/2023	Anti-IL-17A blockade did not significantly reduce inflammatory lesions in a placebo-controlled pilot study in adult patients with moderate to severe acne.
1/2023	Treatment response to isotretinoin correlates with specific shifts in Cutibacterium acnes strain composition within the follicular microbiome.
1/2021	Eligibility Criteria Related to Hormone Therapy in Acne Clinical Trials: A Systematic Review.
10/2016	Efficacy, Safety, and Dermal Tolerability of Dapsone Gel, 7.5% in Patients with Moderate Acne Vulgaris: A Pooled Analysis of Two Phase 3 Trials.
8/2016	Standardized laboratory monitoring with use of isotretinoin in acne.
6/2015	Activity-guided purification identifies lupeol, a pentacyclic triterpene, as a therapeutic agent multiple pathogenic factors of acne.
7/2014	A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: investigating practice gaps and potential cost-savings.
3/2014	Inflammasome activation by Propionibacterium acnes: the story of IL-1 in acne continues to unfold.
2/2014	IL-17: a key player in the P. acnes inflammatory cascade?
2/2013	Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes.

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Diane M Thiboutot Research Topics

Disease

33	Acne Vulgaris 12/2023 - 01/2003
5	Inflammation (Inflammations) 06/2015 - 05/2006
4	Neoplasms (Cancer) 01/2015 - 01/2008
3	Erythema 10/2016 - 11/2004
3	Rosacea (Acne Rosacea) 07/2009 - 04/2005
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023
1	Hypercholesterolemia 08/2016
1	Hypertriglyceridemia 08/2016
1	Pseudotumor Cerebri (Idiopathic Intracranial Hypertension) 01/2016
1	Aneuploidy (Aneuploid) 01/2015
1	Melanoma (Melanoma, Malignant) 01/2015
1	Neoplasm Metastasis (Metastasis) 01/2015
1	Skin Diseases (Skin Disease) 09/2012
1	Breast Neoplasms (Breast Cancer) 07/2010
1	Coronary Artery Disease (Coronary Atherosclerosis) 07/2010
1	Telangiectasis (Telangiectasia) 07/2009
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 01/2008
1	Agranulocytosis (Granulocytopenia) 01/2008
1	Leprosy (Hansen's Disease) 01/2007
1	Dermatitis Herpetiformis (Disease, Duhring's) 01/2007
1	Pruritus (Itching) 11/2004

Drug/Important Bio-Agent (IBA)

11	Isotretinoin (Accutane)FDA LinkGeneric 01/2023 - 01/2003
9	RetinoidsIBA 09/2012 - 11/2004
7	Anti-Bacterial Agents (Antibiotics)IBA 07/2014 - 05/2005
6	Adapalene (Differin)FDA LinkGeneric 06/2008 - 05/2005
4	Benzoyl Peroxide FDA LinkGeneric 11/2010 - 09/2006
3	Hormones (Hormone)IBA 01/2021 - 01/2003
3	Doxycycline (Periostat)FDA LinkGeneric 07/2009 - 05/2005
2	Interleukin-17 (Interleukin 17)IBA 12/2023 - 02/2014
2	Dapsone FDA Link 10/2016 - 01/2007
2	CytokinesIBA 01/2015 - 05/2006
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2012 - 04/2008
2	azelaic acid (Azelex)FDA Link 07/2009 - 06/2008
2	LipidsIBA 05/2009 - 06/2006
2	tazarotene (Tazorac)FDA Link 05/2006 - 11/2004
1	Monoclonal AntibodiesIBA 12/2023
1	Alanine (L-Alanine)FDA Link 08/2016
1	Proteins (Proteins, Gene)FDA Link 06/2015
1	lupeolIBA 06/2015
1	Phosphotransferases (Kinase)IBA 06/2015
1	TriterpenesIBA 06/2015
1	SterolsIBA 06/2015
1	DNA (Deoxyribonucleic Acid)IBA 01/2015
1	ChromatinIBA 01/2015
1	Interleukin-1 (Interleukin 1)IBA 03/2014
1	InflammasomesIBA 03/2014
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 02/2013
1	PolyphenolsIBA 02/2013
1	TeaIBA 02/2013
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 02/2013
1	Toll-Like Receptor 2IBA 09/2012
1	ProdrugsIBA 09/2012
1	Clindamycin (Cleocin)FDA LinkGeneric 11/2010
1	clindamycin phosphate (Clindets)FDA LinkGeneric 11/2010
1	Estrogens (Estrogen)FDA Link 07/2010
1	mahuang-tangIBA 07/2010
1	Progestins (Progestagens)IBA 07/2010
1	Immunoglobulin A (IgA)IBA 07/2009
1	Serine Proteases (Serine Protease)IBA 05/2009
1	Differentiation AntigensIBA 05/2009
1	EnzymesIBA 05/2009
1	Vitamin A (Retinol)FDA LinkGeneric 02/2009
1	Small Interfering RNA (siRNA)IBA 04/2008
1	Lipocalin-2IBA 04/2008
1	Testosterone (Sustanon)FDA Link 01/2008
1	Triglycerides (Triacylglycerol)IBA 01/2008
1	Oral ContraceptivesIBA 01/2008
1	TeratogensIBA 09/2006
1	Minocycline (Cyclops)FDA LinkGeneric 05/2006
1	Granzymes (Granzyme)IBA 05/2006
1	Interleukin-8 (Interleukin 8)IBA 05/2006
1	Matrix Metalloproteinases (MMPs)IBA 05/2006
1	beta-DefensinsIBA 05/2006
1	Antimicrobial PeptidesIBA 05/2006

Therapy/Procedure

15	Therapeutics 12/2023 - 04/2005
1	Duration of Therapy 08/2016